Versión en Español

Contents

Alleged Discrepancies

Article Reprints

Audio Resources

Bible Bullets

Darwin Day Debate

Decisive Designs

E-Books

“In the News”

Reason & Revelation

Research Articles

Scripturally Speaking

Sensible Science

Resources

Discovery for Kids

Examine the Evidence

Home Study Courses

Feedback

EBGlobal

A.P. Information

About AP

Contact AP

Copyright Statement

Help AP

Privacy Statement

Speaking Schedules

A.P. Scientists and
Auxiliary Writers


Usage Guidelines








Apologetics Press :: Sensible Science

“Slugging Out” the Evolutionary Data
by Brad Harrub, Ph.D.

Printer version | Email this article

Scientists frequently find themselves caught between the proverbial “rock and hard place.” On one hand, they work in a “publish or perish” environment in which they must publish data from their labs in prestigious journals, or risk not getting tenured. On the other hand, they must remain faithful to the current dogma of evolution, or risk being labeled as “religious fundamentalists” and have their results called into question. So what happens when a group of researchers has data that screams “creation!,” yet they still need to publish their results? After a great deal of fretting and pacing, they find themselves throwing their arms up, saying, “We realize this looks like evidence for creation, but we know there must be some other explanation”—all the while remaining faithful to evolutionary theory. Occasionally, however, the true picture is evident even when evolutionists have tried to massage the data to better fit their beloved theory. A good example of this appeared in the December 24, 2002 issue of the Proceedings of the National Academy of Sciences (Locascio, et al., 2002). Claiming gene duplication as a major mechanism for increasing genomic complexity and variation during evolution, four researchers from Madrid, Spain, tested gene duplication as a marker for the evolution of vertebrates. Basically, the researchers looked at two genes, slug and snail, and tried to determine how they were passed down the evolutionary tree. However, it is obvious from their own report that they were perplexed by what they found. In the abstract of the report, they stated:

Gene duplication has been a major mechanism for increasing genomic complexity and variation during evolution. The evolutionary history of duplicated genes has been poorly studied along the vertebrate lineage. Here, we attempt to study that history by analyzing the expression of two members of the Snail family, Snail and Slug [genes—BH], in representatives of the major vertebrate groups. We find a surprising degree of variability in a subset of the expression sites for both genes in different species. Although some of the changes can be explained by neofunctionalization or subfunctionalization, others imply reciprocal changes in the expression of the two genes and the reappearance of expression in sites lost earlier in evolution. Because these changes do not fit easily into current models, we need to invoke additional mechanisms acting on enhancer elements to distribute expression domains and functions of duplicated genes unequally during evolution (99:16841, emp. added).

The researchers’ surprise is clearly evident, and even caused them to expand the study to include other organisms in hopes of getting the desired results. They admitted: “We have extended these observations to cartilaginous and bony fishes, reptiles, and turtles, and found a much higher degree of variability in domains of expression for this gene pair than expected” (99:16841, emp. added).

In an effort to draw attention away from the “surprising” findings, and thereby provide the paper with an evolutionary slant, the authors included several series of comparative embryos reminiscent of Ernst Haeckel’s drawings (for a complete discussion on Haeckel’s Hoax see: “Haeckel’s Hoax—CONTINUED!”). The specimens employed were real, not fakes like Haeckel’s, and even the casual observer can see quite clearly a difference between the various species. The images reveal that the slug and snail genes are present in the tail regions of some of the animals, but totally absent in others. For instance, the slug gene is present in the tail bud mesenchyme [primordial embryonic tissue consisting of mesenchymal cells—BH] of the dogfish and chick embryos, but is completely absent from the zebrafish, lizard, turtle, and mouse. Does this mean the chick evolved from the dogfish, or did this gene magically disappear in amphibians, reptiles, and mammals, only to reappear suddenly in birds? In the conclusion of their results the authors commented:

The present analysis of Snail/Slug duplicated genes during vertebrate evolution reveals a much higher degree of plasticity and complexity than expected and highlights the risk of using expression or function as phylogenetic characters when studying the evolution of gene families (99:16845, emp. added).

As they puzzled over how a function could disappear and reappear, they were forced to conclude:

In this case, we would need to invoke extremely unlikely events as the reversal of degenerative mutations or “de novo” creation of tissue-specific regulatory elements to account for the reappearance of these expression domains after their loss at earlier stages in evolution. Although such events may occur over short time-scales, it has such a low probability in our situation that it could be described as an evolutionary reversal, in the sense prohibited by Dollo’s law on the irreversibility of evolutionary changes. A possibility we cannot formally rule out is that ancestors of all of the species analyzed retained expression of both genes in pnc and tail bud, and that independent enhancer loss by mutation occurred in each lineage. In this case, the distribution of expression patterns we observe would not reflect common descent, but random variation. Once more, this is an extremely unlikely scenario, where in all ancestors both duplicated genes were necessarily expressed at all sites simultaneously (99:16845, emp. added).

While they admitted that the distribution of expression patterns they observed “would not reflect common descent,” this did not stop them from including an evolutionary schematic that tried to tie all of these creatures to the same family tree. They then concluded the study by exploring the possibility that epigenetic [the union of sperm and ovum—BH] factors might explain the data, and suggested the possibility that “rare and not parsimonious events can be observed more than once in the evolution of a single genetic regulatory system” (99:16845).

If it walks like a duck, looks like a duck, and quacks like a duck, it must be a duck—unless of course that duck has something to do with supporting the concept of creation. Then, of course, it must be a fish. After all, if the data “do not fit easily into current models, we need to invoke additional mechanisms.” How sad it is that science is no longer a method of obtaining knowledge by reporting and analyzing the data, but rather has become a realm where only the scientific religion of evolution can be propagated and defended.

REFERENCES

Locascio, Annamaria, Miguel Manzanares, Maria J. Blanco, and M. Angela Nieto (2002), “Modularity and Reshuffling of Snail and Slug Expression During Vertebrate Evolution,” Proceedings of the National Academy of Sciences USA, 99:16841-16846, December 24.



Copyright © 2002 Apologetics Press, Inc. All rights reserved.

We are happy to grant permission for items in the "Sensible Science" section to be reproduced in their entirety, as long as the following stipulations are observed: (1) Apologetics Press must be designated as the original publisher; (2) the specific Apologetics Press Web site URL must be noted; (3) the author’s name must remain attached to the materials; (4) any references, footnotes, or endnotes that accompany the article must be included with any written reproduction of the article; (5) alterations of any kind are strictly forbidden (e.g., photographs, charts, graphics, quotations, etc. must be reproduced exactly as they appear in the original); (6) serialization of written material (e.g., running an article in several parts) is permitted, as long as the whole of the material is made available, without editing, in a reasonable length of time; (7) articles, in whole or in part, may not be offered for sale or included in items offered for sale; and (8) articles may be reproduced in electronic form for posting on Web sites pending they are not edited or altered from their original content and that credit is given to Apologetics Press, including the web location from which the articles were taken.

For catalog, samples, or further information, contact:

Apologetics Press
230 Landmark Drive
Montgomery, Alabama 36117
U.S.A.
Phone (334) 272-8558
http://www.apologeticspress.org




Web site engine code is Copyright © 2003 by PHP-Nuke. All Rights Reserved. PHP-Nuke is Free Software released under the GNU/GPL license.
Page Generation: 0.049 Seconds